GETTING MY NAD+ SUPPLEMENTATION AND MITOCHONDRIAL HEALTH TO WORK

Next, we taken care of cells with different concentrations of NAD+. When additional for 24 h at eighty µM in HeLa and four hundred µM in U2OS cells, NAD+ impaired the incorporation of EdU (Fig. 2a and Extended Info Fig. 1k,l). Moreover, 16 µM of NAD+ was adequate to lower fork pace by ~forty% in HeLa cells with out impacting the full lev